abstract：:Obesity is demonstrated to be a risk factor in the development of cancers of various organs, such as colon, prostate, pancreas and so on. Leptine (LEP) is the most renowned of the adipokines. As a hormone, it mediates its effect through leptin receptor (LEPR), which is widely expressed in various tissues including col...

journal_title：PeerJ

authors： Al-Shibli SM,Harun N,Ashour AE,Mohd Kasmuri MHB,Mizan S

更新日期：2019-10-02 00:00:00

abstract：:Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE), which often progresses to end-stage renal disease (ESRD) and ultimately leads to death. At present, there are no definitive therapies towards LN, so that illuminating the molecular mechanism behind the disease has become an urgent ta...

journal_title：PeerJ

authors： Yang H,Li H

更新日期：2019-10-01 00:00:00

abstract：:Exclosures that exclude large herbivores are effective tools for the protection and restoration of grazed plant communities. However, previous studies have shown that the installation of an exclosure does not ensure plant community recovery. Our study aimed to determine the effects of the domination of unpalatable pla...

journal_title：PeerJ

authors： Otsu C,Iijima H,Nagaike T

更新日期：2019-10-01 00:00:00

abstract：Background:Sex ratio distorting agents (maternally inherited symbionts and meiotically-driving sex chromosomes) are common in insects. When these agents rise to high frequencies they create strong population sex ratio bias and selection then favours mutations that act to restore the rare sex. Despite this strong select...

journal_title：PeerJ

authors： Reynolds LA,Hornett EA,Jiggins CD,Hurst GDD

更新日期：2019-10-01 00:00:00

abstract：Background:Vegetation in the Mongolian Plateau is very sensitive to climate change, which has a significant impact on the regulation of terrestrial carbon cycle. Methods:We analyzed spatio-temporal changes of both growing season and the seasonal Normalized Difference Vegetation Index (NDVI) using simple linear trend a...

journal_title：PeerJ

authors： Meng M,Huang N,Wu M,Pei J,Wang J,Niu Z

更新日期：2019-09-30 00:00:00

abstract：Purpose:This study aimed to examine differences between track and field (T&F) runners and foot-orienteers (Foot-O) in the walking and running tests in the absence of vision and hearing. We attempted to determine whether experienced foot orienteers show better ability to maintain the indicated direction compared to trac...

journal_title：PeerJ

authors： Machowska W,Cych P,Siemieński A,Migasiewicz J

更新日期：2019-09-26 00:00:00

abstract：:The orientation of vascular canals in primary bone may reflect differences in growth rate and/or adaptation to biomechanical loads. Previous studies link specific canal orientations to bone growth rates, but results between different taxa are contradictory. Circumferential vascular canals (forming laminar bone) have b...

journal_title：PeerJ

authors： Kuehn AL,Lee AH,Main RP,Simons ELR

更新日期：2019-09-25 00:00:00

abstract：Background:Dengue infection represents a global health issue of growing importance. Dengue non-structural protein 1 (NS1) plays a central role in the early detection of the disease. The most common method for NS1 detection is testing by lateral flow immunoassays (LFIAs) with varying sensitivity. In this study, we prese...

journal_title：PeerJ

authors： Tran TV,Nguyen BV,Nguyen TTP,Tran TT,Pham KG,Le QB,Do BN,Pham HN,Nguyen CV,Dinh DPH,Ha VT,Doan THT,Le HQ

更新日期：2019-09-25 00:00:00

abstract：Background:Chloroplast genomes provide insufficient phylogenetic information to distinguish between closely related sugarcane cultivars, due to the recent origin of many cultivars and the conserved sequence of the chloroplast. In comparison, the mitochondrial genome of plants is much larger and more plastic and could c...

journal_title：PeerJ

authors： Lloyd Evans D,Hlongwane TT,Joshi SV,Riaño Pachón DM

更新日期：2019-09-24 00:00:00

abstract：:The incidence of pediatric cancer is lower than that of adult cancer worldwide. However, the former has detrimental side effects on the health of individuals, even after the cancer is cured, due to the impact of treatment on development. Recently, correlations have been made between the gut microbiome and cancer in se...

journal_title：PeerJ

authors： Sahly N,Moustafa A,Zaghloul M,Salem TZ

更新日期：2019-09-23 00:00:00

abstract：:Melanoma is a global concern and accounts for the major mortality of skin cancers. Herpes simplex virus thymidine kinase gene with ganciclovir (HSV-TK/GCV) is a promising gene therapy for melanoma. Despite its low efficiency, it is well known for its bystander effect which is mainly mediated by gap junction. In this s...

journal_title：PeerJ

authors： Li H,Du H,Zhang G,Wu Y,Qiu P,Liu J,Guo J,Liu X,Sun L,Du B,Tan Y

更新日期：2019-09-20 00:00:00

abstract：:Currently there are 21 shrimp species in the northeastern Atlantic and Mediterranean Sea which are considered to belong to the superfamily Oplophoroidea, but the larval development is unknown for most of them. The complete larval development of Systellaspis debilis (Milne-Edwards, 1881), here described and illustrated...

journal_title：PeerJ

authors： Bartilotti C,Dos Santos A

更新日期：2019-09-18 00:00:00

abstract：:Sex determination and sex chromosomes can be very diverse between teleost species. The group of tilapias shows a polymorphism in sex determination not only between closely related species but also between domestic strains within a species. In the Nile tilapia, the major effect genes and therefore the Y chromosome have...

journal_title：PeerJ

authors： Sissao R,D'Cotta H,Baroiller JF,Toguyeni A

更新日期：2019-09-18 00:00:00

abstract：Background:Much of the shape variation found in animals is based on allometry and heterochrony. Horses represent an excellent model to investigate patterns of size-shape variation among breeds that were intentionally bred for extreme small and large sizes. Methods:We tested whether ponies (wither height < 148 cm) have...

journal_title：PeerJ

authors： Heck L,Sanchez-Villagra MR,Stange M

更新日期：2019-09-16 00:00:00

abstract：Background:Acute respiratory distress syndrome (ARDS) is associated with significantly increased risk of death, and early risk stratification may help to choose the appropriate treatment. The study aimed to develop a neural network model by using a genetic algorithm (GA) for the prediction of mortality in patients with...

journal_title：PeerJ

authors： Zhang Z

更新日期：2019-09-16 00:00:00

abstract：:It has been reported that fermented products (FPs) prepared from sweet potato-shochu distillery by-product suppressed weight gain and decreased serum cholesterol levels in mice under normal dietary conditions. Furthermore, from the information gained from the above data regarding health benefits of the FPs, the aim of...

journal_title：PeerJ

authors： Kosakai T,Kato H,Sho C,Kawano K,Iwai KI,Takase Y,Ogawa K,Nishiyama K,Yamasaki M

更新日期：2019-09-12 00:00:00

abstract：Background and Aim:Water is an increasingly scarce resource while some crops, such as paddy rice, require large amounts of water to maintain grain production. A better understanding of rice drought adaptation and tolerance mechanisms could help to reduce this problem. There is evidence of a possible role of root-associ...

journal_title：PeerJ

authors： Andreo-Jimenez B,Vandenkoornhuyse P,Lê Van A,Heutinck A,Duhamel M,Kadam N,Jagadish K,Ruyter-Spira C,Bouwmeester H

更新日期：2019-09-11 00:00:00

abstract：:Increasing cross-border trade of medicinal and aromatic plants (MAPs) has put heavy pressure on a considerable number of species in the Himalayas. One of the threatened species in Nepal is Aconitum spicatum. Unfortunately for this species and for many others, our knowledge on population ecology and performance across ...

journal_title：PeerJ

authors： Chapagain DJ,Meilby H,Ghimire SK

更新日期：2019-09-10 00:00:00

abstract：Background:The association between asthma (AS), allergic rhinitis (AR) and oral diseases remains inconclusive in adults. AS and AR often coexist. However, studies that investigate AS, AR together and their association with oral diseases are scarce. Methods:Data from 22,898 men and 28,541 women, aged 21 to 25 years, we...

journal_title：PeerJ

authors： Ho SW,Lue KH,Ku MS

更新日期：2019-09-10 00:00:00

abstract：:Okinawa is the largest and most populated island of the Ryukyu Archipelago in southern Japan and is renowned for its natural resources and beauty. Similar as to what has been happening in the rest of the country, Okinawa Island has been affected by an increasing amount of development and construction work. The trend h...

journal_title：PeerJ

authors： Masucci GD,Reimer JD

更新日期：2019-09-06 00:00:00

abstract：:Ortleppascaris sinensis is the dominant nematode species infecting the gastrointestinal tract of the captive Chinese alligator, a critically endangered species. Gastrointestinal nematode infection may cause a loss of appetite, growth, a development disorder, and even mortality in alligators, especially young ones. Thi...

journal_title：PeerJ

authors： Zhao J,Xu W,Tu G,Zhou Y,Wu X

更新日期：2019-09-06 00:00:00

abstract：:Osmia lignaria is a commercially available, native solitary bee species recognized for its propensity to forage upon and pollinate tree fruit crops such as apple, almond and cherry. This study evaluated the implementation of O. lignaria co-pollination with honey bees in central Utah commercial tart cherry orchards dur...

journal_title：PeerJ

authors： Boyle NK,Pitts-Singer TL

更新日期：2019-09-05 00:00:00

abstract：Aim:Historically, the distribution of Sandhill Cranes included much of North America and extending in summer into northeast Russia. In recent years, observations of sandhill cranes in Asia during the non-breeding period have been frequently reported. However, the distribution and abundance of sandhill cranes during the...

journal_title：PeerJ

authors： Gao L,Mi C,Guo Y

更新日期：2019-08-30 00:00:00

abstract：:This study aimed to investigate the effects of Clostridium butyricum as a dietary probiotic supplement in fishmeal based diet on growth, gut microbiota and immune performance of marron (Cherax cainii). Marron were randomly distributed into two different treatment groups, control and probiotic fed group. After 42 days ...

journal_title：PeerJ

authors： Foysal MJ,Nguyen TTT,Chaklader MR,Siddik MAB,Tay CY,Fotedar R,Gupta SK

更新日期：2019-08-27 00:00:00

abstract：:Schemes to reduce road impacts on amphibians have been implemented for decades in Europe, yet, several aspects on the effectiveness of such schemes remain poorly understood. Particularly in northern Europe, including Sweden, there is a lack of available information on road mitigation for amphibians, which is hampering...

journal_title：PeerJ

authors： Helldin JO,Petrovan SO

更新日期：2019-08-26 00:00:00

abstract：:Transgenerational effects are important for phenotypic plasticity and adaptation of marine invertebrates in the changing ocean. Ultraviolet-B (UV-B) radiation is an increasing threat to marine invertebrates. For the first time, we reported positive and negative transgenerational effects of UV-B radiation on egg size, ...

journal_title：PeerJ

authors： Ding J,Zhang L,Sun J,Shi D,Chi X,Yang M,Chang Y,Zhao C

更新日期：2019-08-26 00:00:00

abstract：Background:Biopesticides based on strains of the bacterium Bacillus thuringiensis (Bt) are used globally for effective and environmentally friendly pest control. The most serious threat to the sustainable use of these microbial pesticides is the development of resistance on targeted pests. Populations of Plutella xylos...

journal_title：PeerJ

authors： Baragamaarachchi RY,Samarasekera JKRR,Weerasena OVDSJ,Lamour K,Jurat-Fuentes JL

更新日期：2019-08-23 00:00:00

abstract：:The genus Corbicula consists of estuarine or freshwater clams native to temperate/tropical regions of Asia, Africa, and Australia that collectively encompass both sexual species and clonal (androgenetic) lineages. The latter have become globally invasive in freshwater systems and they represent some of the most succes...

journal_title：PeerJ

authors： Haponski AE,Ó Foighil D

更新日期：2019-08-22 00:00:00

abstract：:Barnacles and their allies (Thecostraca) are a biologically diverse, monophyletic crustacean group, which includes both intensely studied taxa, such as the acorn and stalked barnacles, as well as cryptic taxa, for example, Facetotecta. Recent efforts have clarified phylogenetic relationships in many different parts of...

journal_title：PeerJ

authors： Ewers-Saucedo C,Owen CL,Pérez-Losada M,Høeg JT,Glenner H,Chan BKK,Crandall KA

更新日期：2019-08-16 00:00:00

abstract：:Phlorotannins are primary and/or secondary metabolites found exclusively in brown seaweeds, but their geographic distribution and abundance dynamic are not very well understood. In this study we evaluated the phlorotannin concentrations among and within-species of brown seaweeds in a broad latitudinal context (range o...

journal_title：PeerJ

authors： Ank G,da Gama BAP,Pereira RC

更新日期：2019-08-14 00:00:00

abstract：:Ocean warming threatens the functioning of coral reef ecosystems by inducing mass coral bleaching and mortality events. The link between temperature and coral bleaching is now well-established based on observations that mass bleaching events usually occur when seawater temperatures are anomalously high. However, times...

journal_title：PeerJ

authors： DeCarlo TM,Harrison HB

更新日期：2019-08-12 00:00:00

abstract：:Global warming can significantly affect many aspects of the biology of animal species, including their thermal physiology and physiological performance. Thermal performance curves provide a heuristic model to evaluate the impacts of temperature on the ecophysiology of ectotherms. When integrated with other thermal bio...

journal_title：PeerJ

authors： Cabezas-Cartes F,Fernández JB,Duran F,Kubisch EL

更新日期：2019-08-09 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most heterogeneous malignant cancers with no effective targets and treatments. However, the molecular pathogenesis of HCC remains largely uncertain. The aims of our study were to find crucial genes involved in HCC through multidimensional methods and revealed potential mole...

journal_title：PeerJ

authors： Liu ZK,Zhang RY,Yong YL,Zhang ZY,Li C,Chen ZN,Bian H

更新日期：2019-08-08 00:00:00

abstract：:It is an important issue whether microorganisms can live harmoniously with normal cells in the cardiovascular system. The answer to the question will have enormous impact on medical microbiology. To address the issue, it is essential to identify and characterize the bloodborne microbes in an efficient and comprehensiv...

journal_title：PeerJ

authors： Chiu KP,Yu AL

更新日期：2019-08-06 00:00:00

abstract：:Dung beetles of the subfamily Scarabaeinae are widely recognised as important providers of multiple ecosystem services and are currently experiencing revisions that have improved our understanding of higher-level relationships in the subfamily. However, the study of phylogenetic relationships at the level of genus or ...

journal_title：PeerJ

authors： Pardo-Diaz C,Lopera Toro A,Peña Tovar SA,Sarmiento-Garcés R,Sanchez Herrera M,Salazar C

更新日期：2019-08-05 00:00:00

abstract：:The mitochondrial genome (mitogenome) sequence of the tree frog Polypedates megacephalus (16,473 bp) was previously reported as having the unusual characteristic of lacking the ND5 gene. In this study, a new mitogenome of P. megacephalus (19,952 bp) was resequenced using the next-generation sequencing (NGS) and standa...

journal_title：PeerJ

authors： Huang A,Liu S,Li H,Luo H,Ni Q,Yao Y,Xu H,Zeng B,Li Y,Wei Z,Li S,Zhang M

更新日期：2019-08-01 00:00:00

abstract：:The study investigates the solution of the multicollinearity between certain body measurements of Romanov lambs and prediction of the body weight of Romanov lambs using the thus calculated factor analysis scores and a multiple regression model. For this purpose, the body measurements (wither height (WH), croup height ...

journal_title：PeerJ

authors： Tahtali Y

更新日期：2019-08-01 00:00:00

abstract：:Pathogens invading the mammary gland are recognized through a range of pattern recognition receptors (PRRs), residing on the plasma membrane of mammary epithelial cells. Toll-like receptor 2 (TLR2) signalling is responsible for recognition of Gram-positive bacteria, which are the most common mastitis-causing pathogens...

journal_title：PeerJ

authors： Ogorevc J,Simčič M,Zorc M,Škrjanc M,Dovč P

更新日期：2019-07-31 00:00:00

abstract：:The octopus fauna from the southern Caribbean is an understudied field. However, recent taxonomic work in the Colombian Caribbean has led to the discovery of several new species in the family Octopodidae. To provide molecular evidence for recent descriptions in the area (i.e., Octopus taganga, O. tayrona and Macrotrit...

journal_title：PeerJ

authors： Ritschard EA,Guerrero-Kommritz J,Sanchez JA

更新日期：2019-07-29 00:00:00

abstract：Background:Self-efficacy and enjoyment are two main constructs proposed within many motivational theories in any human endeavor, sport and physical activity included. Methods:The purpose of this study was to examine the factor structure of two pictorial scales measuring self-efficacy and enjoyment levels in a sample o...

journal_title：PeerJ

authors： Morano M,Bortoli L,Ruiz MC,Vitali F,Robazza C

更新日期：2019-07-29 00:00:00